University of Hawai‘i
Research Compliance

Collaborative Research

For research in which two or more FWA-holding institutions are engaged in a research protocol/proposal, investigators may request to have UH IRB be the relying IRB or cede IRB authority to another IRB. For more information, see SOP 120: Collaborative Research.

Ceding agreement in which UH IRB is the reviewing IRB
Step One: Download and complete the IRB Authorization Agreement form

Reviewing IAA Application

Information you will need:

  • Name of the Other Institution
  • The other institution’s IRB Registration Number (if relying on the another IRB) or FWA # (if using UH IRB as the relying IRB)
  • Project Name
  • Principal Investigator(s) of all Institutions listed in the IAA, with their respective institution’s name in brackets next to the name
  • Funding Source and Award Number, if applicable
  • Name of the Other Institution’s Institutional Official (IO)
  • Title of the Other Institution’s IO

Provide the Local Context Review Form to the relying institutions to complete, if they wish to input any local context consideration, administrative review.

Step Two: Submit the application

Submit the application to HSP via email or hardcopy. As part of your submission, provide a memorandum addressed to the Human Studies Program Director describing the justification for the reviewing request.

Include a copy of the Local Context Review Form, if any.

If you have not already obtained UH IRB approval, submit an IRB application for review. If you have an approval, and are adding a new collaborator or new site, you may need to submit a modification application to your project. Include the HSP number  for the project if available.

Ceding agreement in which UH IRB cedes authority to another IRB (relying)
Step One: Download and complete the IRB Authorization Agreement form

Ceding (Relying) IAA Application

Information you will need:

  • Name of the Other Institution
  • The other institution’s IRB Registration Number (if relying on the another IRB) or FWA # (if using UH IRB as the relying IRB)
  • Project Name
  • Principal Investigator(s) of all Institutions listed in the IAA, with their respective institution’s name in brackets next to the name
  • Funding Source and Award Number, if applicable
  • Name of the Other Institution’s Institutional Official (IO)
  • Title of the Other Institution’s IO
Step Two: Submit the application

Submit the application to HSP via email or hardcopy. As part of your submission, provide a memorandum addressed to the Human Studies Program Director describing the justification for ceding authority to another IRB.

Include a copy of the protocol, and informed consent, especially as relating to local participation

Smart IRB

UH is now a participant in an online reliance system, intended to help standardize and streamline this type of agreement, called Smart IRB. To use Smart IRB, both parties will need to be participants. You will need to check with your collaborator, or check the Smart IRB website to verify. If you do not have one already, you would need to create an account on the Smart IRB platform. You can access the request page at https://smartirb.org/reliance/. Once you have created your account, you can go ahead and start your reliance request on the platform.  You can contact us at the HSP office to have us assist you at that point, as well. Smart IRB may be the most efficient if there are multiple participating sites.

Alternative Forms

Alternatively, use the reliance agreement provided by the other institution. Typically, these agreements include much the same information, and we normally have no problems with using another institution’s agreement form.